A novel flavin derivative reveals the impact of glucose on oxidative stress in adipocytes.
نویسندگان
چکیده
We present the synthesis and characterisation of naphthalimide-flavin redox sensor 1 (NpFR1), a novel flavin molecule that is almost non-fluorescent in reduced form, but oxidation gives rise to a 125-fold increase in fluorescence. Confocal microscopy experiments confirm that is sensitive to redox changes within living cells.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 60 شماره
صفحات -
تاریخ انتشار 2014